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MammoCheck Secures A €500,000 SEED Grant From The RIF To Advance Toward FDA 510(k) Clearance And EU MDR CE Marking

MammoCheck RIF Grant Signed

The project is co-funded by the European Union and the Republic of Cyprus under the Cohesion Policy Programme THALIA 2021–2027. Frederick Research Center is participating as a partner organisation, continuing the company’s roots as a spin-out of Frederick University.

NICOSIA, CYPRUS, July 31, 2026. MammoCheck Ltd, a Cyprus-based medical technology company founded as a spin-out of Frederick University, has secured a €500,000 grant under the Research and Innovation Foundation’s (RIF) SEED programme.

The competitive grant will support the continued development of the company’s adjunctive, research-validated software platform, which combines thermal imaging with artificial intelligence to support breast cancer screening. More specifically, the funding will support the clinical, quality management and regulatory work required as the company advances toward FDA 510(k) clearance in the United States and CE marking under the EU Medical Device Regulation (MDR 2017/745).

The RIF’s SEED programme supports innovative Cypriot start-ups developing internationally competitive products and services. It is co-funded by the European Union through the European Regional Development Fund and the Republic of Cyprus under the Cohesion Policy Programme THALIA 2021–2027.

For MammoCheck, the funding will support completion of its clinical programme, further development of its quality management system in line with ISO 13485, and preparation of the technical documentation and submissions required for the FDA and EU MDR regulatory pathways.

About MammoCheck

MammoCheck is developing a Software as a Medical Device (SaMD) platform that combines a smartphone application, thermal imaging and a proprietary artificial intelligence algorithm to support breast cancer screening.

Founded in 2024 as a spin-out of Frederick University, the company aims to address unequal access to screening. Mammography coverage remains highly uneven worldwide and has been reported as low as 1.7% in some countries, including among many women under the age of 45 who fall outside most national screening programmes.

The platform is being developed for use in primary care and gynaecology settings, as well as for guided home use, with every result reviewed by a clinician. It is intended to complement, rather than replace, established imaging modalities such as mammography and ultrasound.

MammoCheck is currently conducting a clinical study across hospital sites in Cyprus, approved by the Cyprus National Bioethics Committee.

The Role Of Frederick University

Frederick University continues to support the initiative as the institution from which MammoCheck originated. The collaboration also continues through the participation of the Frederick Research Center as a partner organisation in the funded project.

The centre contributes specialised expertise and infrastructure through its Nursing Department and the Mobile Devices Laboratory, focusing on artificial intelligence, smart systems and scientific dissemination. The collaboration strengthens the connection between Cypriot academic research and internationally oriented innovation.

The Frederick team supporting the project includes Dr. Andreas Constantinides, Associate Professor and Director of the Mobile Devices Laboratory, Dr. Evanthia Asimakopoulou, Assistant Professor in the Nursing Department, and Dr. Elena Papoui, Visiting Lecturer in the Nursing Department.

What The Grant Means

The award adds to a period of continued momentum for the company. Alongside its clinical and regulatory progress, MammoCheck is conducting a private investment round to accelerate commercial deployment as it advances toward key regulatory milestones.

The company also holds a Certificate of Innovative Enterprise from the Cyprus Deputy Ministry of Research, Innovation and Digital Policy, allowing eligible investors participating in the funding round to benefit from tax incentives under Cyprus’ innovation investment legislation.

Statements

“Securing €500,000 in competitive, non-dilutive funding is a strong vote of confidence in our vision, our team and our mission. It allows us to focus on what truly matters right now, turning that vision into reality, step by step, as we move steadily toward FDA 510(k) clearance and CE marking under the EU MDR,” said Alexandra Dimitriadou, Co-Founder and CEO of MammoCheck.

Athina Grigoriou, Co-Founder and CRO, added: “Our clinical programme is at the heart of this project. This support strengthens the study we are conducting across hospital sites in Cyprus and the evidence base behind every step of our regulatory pathway.”

Marios Pafitis, Co-Founder and CTO, said: “Working alongside the Frederick Research Center brings academic rigour to our engineering. This grant helps us take the technology from promising research toward a rigorously engineered and clinically validated product.”

The MammoCheck co-founding team, Alexandra Dimitriadou, Marios Pafitis and Athina Grigoriou, was named to the Forbes 30 Under 30 Greece list in 2026.

The MAMMOCHECK project (SEED/0525(B)/0102) is implemented under the Cohesion Policy Programme THALIA 2021–2027 and is co-funded by the European Union through the European Regional Development Fund and the Republic of Cyprus via the Research and Innovation Foundation.

Cyprus Steps Up Efforts To Attract U.S. Tech Investment And Talent

Cyprus is preparing a renewed push to attract U.S. technology companies, investment and skilled professionals, with President Nikos Christodoulides expected to lead a delegation to the United States at the end of November 2026.

The visit will build on contacts made during the president’s April 2025 trip and focus on turning interest from the U.S. technology ecosystem into business partnerships, investment and opportunities for Cypriot professionals abroad. A central part of the effort is a New York event on Nov. 30, organized by the Presidency and Invest Cyprus under the “Minds in Cyprus – The Brain Gain Initiative.”

The initiative is designed to connect Cypriots working in the United States with companies operating in Cyprus that are seeking specialized talent. It also reflects a wider economic challenge: attracting technology businesses is difficult if the country cannot provide enough experienced professionals to support their growth.

Building On Earlier U.S. Engagement

The upcoming mission follows a series of meetings in the United States in April 2025, when Christodoulides met representatives of major companies, including Nvidia, Amazon, Google, OpenAI, Tenstorrent and Plug and Play.

Since then, Plug and Play and Tenstorrent have opened offices in Cyprus. The engagement with Nvidia has also been significant, although the company has not established an office on the island. The collaboration contributed to the development of computing infrastructure and the installation and operation of Cyprus’s first operational supercomputer.

Contacts with other technology companies, including Amazon, Google, OpenAI, Oracle and Microsoft, have continued since the 2025 meetings. Interest appears to be ongoing: the president of Invest Cyprus recently said that two additional U.S. companies had approached the organization seeking information about establishing operations in the country.

Turning Business Contacts Into Investment

The government’s aim is to build on the momentum of the previous visit and convert engagement with U.S. businesses and technology leaders into concrete commercial outcomes. Christodoulides has said that meetings with Cypriot scientists and entrepreneurs in technology and innovation helped inspire Cyprus Catalyst, a network intended to connect Cypriot professionals in the United States with the country’s business community.

The network is designed to create channels for collaboration, investment and growth between Cyprus and the U.S. technology ecosystem. The president has emphasized that international outreach should lead to tangible partnerships and economic opportunities, rather than remain a series of diplomatic or business contacts.

Investment And The Brain-Gain Strategy

Attracting foreign companies is only one part of the government’s strategy. The other is encouraging Cypriot scientists and professionals living abroad to return, bringing skills and experience gained in international markets.

The two goals are closely linked. New technology companies create demand for specialized employees; returning professionals can help meet that demand. For Cyprus, the availability of skilled workers is also a factor in whether prospective investors decide to establish operations on the island.

The Nov. 30 event in New York will bring together Cypriot professionals working in the United States, entrepreneurs, corporate executives and members of the wider Cyprus-U.S. business community. Its purpose is to present the professional opportunities emerging in Cyprus and connect attendees with organizations seeking people with specific expertise.

What Participants Can Expect

According to the published program, attendees will be able to:

  • Learn about current and expected job openings in Cyprus and meet representatives of local businesses.
  • Take part in one-to-one matchmaking meetings with companies seeking professionals with specific skills and experience.
  • Hear about developments in the Cypriot economy, priority growth sectors, investment opportunities and the business environment.
  • Review the government’s Action Plan for the Repatriation of Talent and the options available to professionals considering a return.
  • Build professional connections with Cypriot scientists, entrepreneurs and members of the broader U.S.–Cyprus business community.

The mission’s broader test will be whether Cyprus can translate international interest into sustained investment—and pair that investment with the talent needed to support long-term growth.

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