Cyprus and Israel Join Forces For Groundbreaking Gene Editing Project

by News Editor

March 31, 2025

The Molecular Genetics Thalassaemia Department at the Cyprus Institute of Neurology & Genetics (CING) has launched EDIT-4-IRON, an ambitious genome editing initiative aimed at transforming treatments for iron-related blood disorders.

Backed by a €200,000 grant under the “RESTART 2016–2020, Bilateral Collaborations” program from the Research and Innovation Foundation, this 36-month project strengthens scientific ties between Cyprus and Israel while reinforcing both nations’ positions as leaders in genetic and haematological research.

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A Pioneering Collaboration

Led by Dr. Carsten W. Lederer, Head of the MGTD and Associate Professor at CING, the Cypriot team includes haematologist Dr. Panayiota L. Papasavva and gene editing expert Dr. Petros Patsali. On the Israeli side, gene editing specialist Dr. Ayal Hendel, a professor at Bar-Ilan University (BIU), spearheads the project.

Both institutions bring extensive expertise to the table. CING, the national reference laboratory for rare anaemia research and diagnosis in Cyprus, has been at the forefront of gene therapy innovations. BIU, meanwhile, holds multiple patents in editing technology and is a national leader in advanced therapy medicinal product development for blood disorders.

Training The Next Generation

Beyond its scientific breakthroughs, EDIT-4-IRON will provide cutting-edge training opportunities. The project supports two PhD students—one in Cyprus (Azzam Mohamed Ahmed Abdelfattah) and one in Israel—alongside an MSc student in Israel, offering them hands-on experience in gene therapy technologies and international networking prospects.

A Revolutionary Approach To Iron Disorders

EDIT-4-IRON aims to revolutionise treatments for inherited and acquired iron-related haematological disorders (IHDs), such as transfusion-dependent β-thalassaemia, non-transfusion-dependent thalassaemia, hereditary haemochromatosis, and polycythaemia vera. These conditions, often marked by iron overload or ineffective erythropoiesis, currently rely on small-molecule therapies that require lifelong administration and come with significant side effects.

By leveraging CRISPR/Cas and base editing technologies, researchers aim to create gene knockouts that induce an iron-restrictive state, potentially offering a long-term therapeutic alternative for thousands of patients worldwide.

A Data-Driven Approach

The project will rigorously evaluate the safety and efficacy of these gene-editing strategies through ex vivo and in vivo testing, using primary patient samples from Cyprus, cell lines, and murine disease models. This approach ensures that any breakthroughs can be translated into real-world clinical applications.

Setting the Stage For Innovation

EDIT-4-IRON officially kicked off on May 26, 2025, with a meeting between the Cypriot and Israeli teams to define collaboration frameworks, project milestones, and deliverables. With its combination of groundbreaking science, international cooperation, and a commitment to patient-centric innovation, this project marks a significant step forward in the fight against iron-related blood disorders.

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Cypriots Report Growing Economic Concerns In New Eurobarometer Survey

by THEFUTURE.TEAM

May 11, 2026

Eurobarometer Survey Reveals Stark Economic Outlook

A comprehensive Eurobarometer survey conducted between March 12 and April 1, 2026, has revealed significant economic and institutional challenges in Cyprus ahead of Europe Day. The study, which included 506 interviews in Cyprus as part of a pan-European sample of 26,415 citizens, underscores a pronounced economic pessimism and declining trust in national and European institutions.

Economic Sentiment And Future Projections

More than half of Cypriots, or 53%, described the country’s economic situation negatively, while 46% expressed a positive assessment. Across the European Union, by comparison, 60% of respondents viewed their national economies positively and 38% negatively.

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Economic pessimism also increased sharply compared with autumn 2025. Around 51% of Cypriots said they expect the economy to deteriorate further over the next year, marking a 23 percentage point increase from the previous survey period. Only 11% anticipated economic improvement.

Despite broader concerns about the economy, perceptions of personal financial conditions remained relatively stable. Around 75% of respondents described their household financial situation positively, while 60% said they expect employment conditions to remain stable over the coming year.

Main Challenges And Priorities For Action

The cost of living remained the leading concern among Cypriot respondents at 36%, followed by developments in the Middle East at 30%, the national economy at 24%, migration at 23% and housing at 21%. Across the EU more broadly, respondents prioritised instability in the Middle East, Russia’s invasion of Ukraine and migration.

Regarding policy priorities, Cypriots said EU spending should focus primarily on employment, social policy and healthcare, alongside education, youth initiatives, housing and security.

Institutional Distrust And European Identity

Trust in national institutions remained low throughout the survey. Only 31% of respondents said they trust the government, while confidence in parliament stood at 22%. At the same time, 74% expressed distrust toward parliament.

Views toward the European Union also remained divided. Around 39% of Cypriots said they trust the EU, compared with 54% who said they do not, although this represented a slight improvement from autumn 2025.

The survey additionally pointed to a stronger sense of local and national identity than European identity. While 92% said they feel connected to their local communities and 95% to Cyprus itself, only 52% reported feeling attached to the EU and 45% identified with Europe more broadly.

Digital Security And Divergent Foreign Policy Views

Concerns about digital safety also remained elevated, with 53% of respondents saying major online platforms are not doing enough to remove illegal or harmful content. Another 45% said existing user protection measures remain insufficient.

The survey also revealed notable differences between Cypriot and wider EU attitudes toward the war in Ukraine. Although 77% supported accepting refugees and 70% backed humanitarian and economic assistance, support for sanctions against Russia stood at only 30%, significantly below the EU average.

Support for military assistance to Kyiv remained particularly low at 18%, while only 41% of respondents supported Ukraine’s future EU membership compared with 56% across the bloc.

Conclusion

The findings reflect growing economic anxiety and continued institutional scepticism in Cyprus amid broader geopolitical uncertainty across Europe and the Middle East. At the same time, the survey showed that Cypriots remain highly focused on domestic economic stability, social policy and cost-of-living pressures as key priorities for the years ahead.

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