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Cyprus and Israel Join Forces For Groundbreaking Gene Editing Project

by News Editor

March 31, 2025

The Molecular Genetics Thalassaemia Department at the Cyprus Institute of Neurology & Genetics (CING) has launched EDIT-4-IRON, an ambitious genome editing initiative aimed at transforming treatments for iron-related blood disorders.

Backed by a €200,000 grant under the “RESTART 2016–2020, Bilateral Collaborations” program from the Research and Innovation Foundation, this 36-month project strengthens scientific ties between Cyprus and Israel while reinforcing both nations’ positions as leaders in genetic and haematological research.

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A Pioneering Collaboration

Led by Dr. Carsten W. Lederer, Head of the MGTD and Associate Professor at CING, the Cypriot team includes haematologist Dr. Panayiota L. Papasavva and gene editing expert Dr. Petros Patsali. On the Israeli side, gene editing specialist Dr. Ayal Hendel, a professor at Bar-Ilan University (BIU), spearheads the project.

Both institutions bring extensive expertise to the table. CING, the national reference laboratory for rare anaemia research and diagnosis in Cyprus, has been at the forefront of gene therapy innovations. BIU, meanwhile, holds multiple patents in editing technology and is a national leader in advanced therapy medicinal product development for blood disorders.

Training The Next Generation

Beyond its scientific breakthroughs, EDIT-4-IRON will provide cutting-edge training opportunities. The project supports two PhD students—one in Cyprus (Azzam Mohamed Ahmed Abdelfattah) and one in Israel—alongside an MSc student in Israel, offering them hands-on experience in gene therapy technologies and international networking prospects.

A Revolutionary Approach To Iron Disorders

EDIT-4-IRON aims to revolutionise treatments for inherited and acquired iron-related haematological disorders (IHDs), such as transfusion-dependent β-thalassaemia, non-transfusion-dependent thalassaemia, hereditary haemochromatosis, and polycythaemia vera. These conditions, often marked by iron overload or ineffective erythropoiesis, currently rely on small-molecule therapies that require lifelong administration and come with significant side effects.

By leveraging CRISPR/Cas and base editing technologies, researchers aim to create gene knockouts that induce an iron-restrictive state, potentially offering a long-term therapeutic alternative for thousands of patients worldwide.

A Data-Driven Approach

The project will rigorously evaluate the safety and efficacy of these gene-editing strategies through ex vivo and in vivo testing, using primary patient samples from Cyprus, cell lines, and murine disease models. This approach ensures that any breakthroughs can be translated into real-world clinical applications.

Setting the Stage For Innovation

EDIT-4-IRON officially kicked off on May 26, 2025, with a meeting between the Cypriot and Israeli teams to define collaboration frameworks, project milestones, and deliverables. With its combination of groundbreaking science, international cooperation, and a commitment to patient-centric innovation, this project marks a significant step forward in the fight against iron-related blood disorders.

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Cyprus’ Strong Youth Employment Rate Still Does Not Guarantee Early Independence

by THEFUTURE.TEAM

September 16, 2026

Young people in Cyprus have a relatively high employment rate, but they leave the parental home later than the EU average, according to Eurostat data.

Cypriots left home at an average age of 27 in 2025, compared with 26.3 years across the EU. At the same time, 72.3% of people aged 20 to 29 in Cyprus were employed, well above the EU average of 65.5%.

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Strong Employment Does Not Mean Early Independence

Only nine countries recorded higher youth employment rates than Cyprus. Iceland led at 85.3%, followed by the Netherlands at 84%, Malta at 82.1%, Switzerland at 78.3% and Germany at 77%.

Norway recorded 76.5%, Ireland 76.1%, Denmark 74.8% and Austria 74.6%. Eurostat said countries where young people leave home earlier generally tend to have higher youth employment rates.

Southern Europe Sees Later Moves

Finland had the lowest average age for leaving the parental home at 21.4 years, followed by Denmark at 21.8 and Estonia and Lithuania at 22.7. Croatia recorded the highest average at 31.5 years, followed by Greece and Slovakia at 30.9. Spain and Italy both stood at 30.2 years.

Across the EU, the average has remained close to 26 since 2002, rising only slightly from 26.2 years in 2024 to 26.3 years in 2025.

Cyprus Labour Market Is Cooling

The figures come as Cyprus’ labor market shows some signs of easing, although demand for workers remains relatively strong by European standards.

Separate Eurostat data showed Cyprus had the EU’s largest annual decline in its job vacancy rate in the second quarter of 2026. The rate fell to 2.6% from 3.3% a year earlier, but remained above the EU average of 2.0% and the euro area average of 2.1%.

Cost Of Living Remains A Factor

Housing and other living costs can also affect how quickly young workers establish independent households. Eurostat reported that Cyprus’ household consumption price level was 89.2% of the EU average in 2025.

A relatively lower overall price level does not eliminate affordability pressures for people on modest incomes. For younger workers, the issue can be whether wages are sufficient to cover rent, utilities, food and other basic expenses.

Cyprus therefore combines relatively high youth employment with a later transition to independent living, suggesting that access to work and the ability to afford a separate household do not always move together.